Systems and methods for handling wellsite packets for a wellsite are provided. The wellsite packets include soluble packaging with wellsite materials therein. The wellsite has surface equipment and downhole equipment positioned about a wellbore. The handling system includes at least one feeder, at least one mixer, at least one metering device, and a pump. The feeder moves the wellsite packets directly or indirectly into the mixer. The mixer stimulates dissolution of the soluble packaging so as to mix the wellsite materials with a fluid to form a wellsite mixture. The metering device selectively controls the number of wellsite packets moving to the mixer. The pump is operatively coupled to the mixer to pump the wellsite mixture at the wellsite.