Invention Grant
- Patent Title: Method for the treatment of cardiovascular fibrosis
- Patent Title (中): 治疗心血管纤维化的方法
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Application No.: US14426563Application Date: 2013-09-27
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Publication No.: US09594083B2Publication Date: 2017-03-14
- Inventor: Frederic Jaisser , Nicolette Farman , Antoine Tarjus , Patrick Rossignol , Faiez Zannad
- Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale) , Universite de Lorraine , Centre Hospitalier et Universitaire de Nancy (CHU) , Universite Paris Diderot-Paris 7 , Universite Paris Descartes
- Applicant Address: FR Paris FR Nancy FR Nancy FR Paris FR Paris
- Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale),Universite de Lorraine,Cantre Hospitalier et Universitaire de Nancy (CHU),Universite Paris Diderot-Paris 7,Universite Paris Descartes
- Current Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale),Universite de Lorraine,Cantre Hospitalier et Universitaire de Nancy (CHU),Universite Paris Diderot-Paris 7,Universite Paris Descartes
- Current Assignee Address: FR Paris FR Nancy FR Nancy FR Paris FR Paris
- Agency: Whitham, Curtis & Cook, P.C.
- Priority: EP12306178 20120928
- International Application: PCT/EP2013/070277 WO 20130927
- International Announcement: WO2014/049152 WO 20140403
- Main IPC: A61K31/7088
- IPC: A61K31/7088 ; A61K31/7105 ; A61K31/713 ; A61K47/48 ; C07K14/47 ; G01N33/573 ; C12N15/113 ; C12N15/115
Abstract:
The present invention relates to methods and pharmaceutical compositions for the treatment of cardiovascular fibrosis. In particular, the present invention relates to an inhibitor of Neutrophil Gelatinase-Associated Lipocalin (NGAL) activity or expression for use in a method for treating or preventing cardiovascular fibrosis in a subject in need thereof.
Public/Granted literature
- US20150247855A1 Methods and Pharmaceutical Compositions for the Treatment of Cardiovascular Fibrosis Public/Granted day:2015-09-03
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