Method and apparatus for analyzing a document against a managed research domain are provided. In one embodiment, a managed research domain provides an infrastructure where logical statements in research documents stored in the research domain repository are quantified and semantically analyzed. A user may submit a draft research document for analysis against the managed research domain to compare the draft against the current research knowledge in particular topics. The draft research document is annotated to reflect how the logical statements in the draft compare to the statements made on similar topics in the managed research domain.