A system for sharing an optical fiber for a cloud-based wired and wireless access network, includes: a centralization device to generate summing signals by respectively summing multi-channel optical signals input from a wireless donor unit group and by summing multi-channel wired signals input from a wired donor unit group or generate wavelength-converted signals by wavelength-converting the multi-channel optical signals or the multi-channel wired signals, multiplex the summing signals or the wavelength-converted signals, and distribute the summing signals or the wavelength-converted signals to a plurality of devices connected to the centralization device via a shared optical fiber; and a distribution device group to generate corresponding optical signals by demultiplexing the summing signals or the wavelength-converted signals in units of wavelengths, and transmit the corresponding optical signals or the multi-channel wired signals to a wireless remote unit group and/or a wired remote unit group via a preset optical fiber.