Systems and methods are described for transmitting data over physical channels to provide a high bandwidth, low latency interface between a transmitting device and a receiving device operating at high speed with low power utilization. Communication is performed using group signaling over sets of four wires using a vector signaling code, where each wire of a set carries a low-swing signal that may take on one of four signal values. Topologies and designs of wire sets are disclosed with preferred characteristics for group signaling communications.