Invention Grant
- Patent Title: Combination of dofetilide and mexiletine for the prevention and treatment of atrial fibrillation
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Application No.: US14922529Application Date: 2015-10-26
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Publication No.: US09597302B1Publication Date: 2017-03-21
- Inventor: Ganxin Yan , Jian-Zeng Dong , Chang-Sheng Ma
- Applicant: Heart Rhythm Solutions, Inc.
- Applicant Address: US PA Newtown Square
- Assignee: Heart Rhythm Solutions, Inc.
- Current Assignee: Heart Rhythm Solutions, Inc.
- Current Assignee Address: US PA Newtown Square
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Main IPC: A61K31/18
- IPC: A61K31/18 ; A61K31/138 ; A61K9/00 ; A61K9/48
Abstract:
Effective and safe pharmaceutical composition and method for treating atrial fibrillation are described. The combined use of dofetilide and mexiletine resulted in an enhanced efficacy in the prevention and treatment of atrial fibrillation with markedly reduced risk of the life-threatening ventricular arrhythmia TdP.
Public/Granted literature
- US20170087105A1 COMBINATION OF DOFETILIDE AND MEXILETINE FOR THE PREVENTION AND TREATMENT OF ATRIAL FIBRILLATION Public/Granted day:2017-03-30
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