- Patent Title: Inhibitors of late SV40 factor (LSF) as cancer chemotherapeutics
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Application No.: US13879106Application Date: 2011-09-30
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Publication No.: US09597325B2Publication Date: 2017-03-21
- Inventor: Ulla Hansen , Scott Schaus , Trevor Grant , Joshua Bishop , John Kavouris , Lisa M. Christadore
- Applicant: Ulla Hansen , Scott Schaus , Trevor Grant , Joshua Bishop , John Kavouris , Lisa M. Christadore
- Applicant Address: US MA Boston
- Assignee: Trustees of Boston University
- Current Assignee: Trustees of Boston University
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- International Application: PCT/US2011/054305 WO 20110930
- International Announcement: WO2012/050985 WO 20120419
- Main IPC: A61K31/4741
- IPC: A61K31/4741 ; A61K31/4704
Abstract:
The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a small-molecule compound of formulas (I)-(XXVI) as disclosed herein to inhibit transcription factor Late SV40 Factor (LSF) for treatment of cancer, e.g., HCC.
Public/Granted literature
- US20130324570A1 INHIBITORS OF LATE SV40 FACTOR (LSF) AS CANCER CHEMOTHERAPEUTICS Public/Granted day:2013-12-05
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