- Patent Title: Compositions for treating obesity and insulin resistance disorders
-
Application No.: US14460397Application Date: 2014-08-15
-
Publication No.: US09597347B2Publication Date: 2017-03-21
- Inventor: David A. Sinclair , Maria Alexander-Bridges
- Applicant: President and Fellows of Harvard College , The General Hospital Corporation
- Applicant Address: US MA Cambridge US MA Boston
- Assignee: President and Fellows of Harvard College,The General Hospital Corporation
- Current Assignee: President and Fellows of Harvard College,The General Hospital Corporation
- Current Assignee Address: US MA Cambridge US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/706 ; A61K31/00 ; A61K31/05 ; A61K31/12 ; A61K31/353 ; A61K31/7048 ; A61K45/06 ; A61K31/7052 ; A61K31/455
Abstract:
Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.
Public/Granted literature
- US20150133396A1 COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS Public/Granted day:2015-05-14
Information query
