Invention Grant
- Patent Title: Vault complexes for cytokine delivery
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Application No.: US14553146Application Date: 2014-11-25
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Publication No.: US09597372B2Publication Date: 2017-03-21
- Inventor: Leonard H. Rome , Valerie A. Kickhoefer , Steven M. Dubinett , Sherven Sharma , Upendra K. Kar
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland US DC Washington
- Assignee: The Regents of the University of California,The United States of America as represented by the Department of Veterans Affairs
- Current Assignee: The Regents of the University of California,The United States of America as represented by the Department of Veterans Affairs
- Current Assignee Address: US CA Oakland US DC Washington
- Agency: Canady + Lortz LLP
- Agent Suzannah K. Sundby, Esq.
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12P21/06 ; C07K14/435 ; A61K38/19 ; A61K38/00 ; C07K14/52 ; A61K47/48 ; A61K35/12 ; A61K48/00 ; C07H21/00 ; C07K7/06 ; C07K14/47 ; C12N5/0783 ; C12N9/96 ; C12N15/86 ; G01N33/535
Abstract:
The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
Public/Granted literature
- US20150150944A1 Vault Complexes for Cytokine Delivery Public/Granted day:2015-06-04
Information query
