Invention Grant
- Patent Title: Cyclic-dinucleotides and its conjugates as adjuvants and their uses in pharmaceutical compositions
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Application No.: US12092747Application Date: 2006-11-08
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Publication No.: US09597391B2Publication Date: 2017-03-21
- Inventor: Thomas Ebensen , Michael Morr , Carlos A. Guzman
- Applicant: Thomas Ebensen , Michael Morr , Carlos A. Guzman
- Applicant Address: DE Braunschweig
- Assignee: HELMHOLTZ_ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH
- Current Assignee: HELMHOLTZ_ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH
- Current Assignee Address: DE Braunschweig
- Agency: Whitham, Curtis & Cook, P.C.
- Priority: EP05024266 20051108
- International Application: PCT/EP2006/010693 WO 20061108
- International Announcement: WO2007/054279 WO 20070518
- Main IPC: A61K39/39
- IPC: A61K39/39 ; A61K39/00 ; A61P37/00 ; A61K31/7084 ; A61K31/7076
Abstract:
The present invention relates to new adjuvants and the uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new compounds useful as adjuvants and/or immunomodulators for prophylactic and/or therapeutic vaccination in the treatment of infectious diseases, inflammatory diseases, autoimmune diseases, tumors, allergies as well as for the control of fertility in human or animal populations. The compounds are particularly useful not only as systemic, but preferably as mucosal adjuvants. In addition, the invention relates to its uses as active ingredients in pharmaceutical compositions.
Public/Granted literature
- US20080286296A1 Cyclic-Dinucleotides and Its Conjugates as Adjuvants and Their Uses in Pharmaceutical Compositions Public/Granted day:2008-11-20
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