Invention Grant
- Patent Title: Process for preparing cinacalcet and pharmaceutically acceptable salts thereof
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Application No.: US15075268Application Date: 2016-03-21
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Publication No.: US09598350B2Publication Date: 2017-03-21
- Inventor: Jean-Marie Schneider , Jonathan Madec , Sergio Kreimerman , Gerard Guillamot
- Applicant: Produits Chimiques Auxiliaires et de Synthese
- Applicant Address: FR Longjumeau
- Assignee: Produits Chimiques Auxiliaries et de Synthese
- Current Assignee: Produits Chimiques Auxiliaries et de Synthese
- Current Assignee Address: FR Longjumeau
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: FR1258408 20120907
- Main IPC: C07C209/68
- IPC: C07C209/68 ; C07C209/84 ; C07C209/52 ; C07C211/30 ; C07C249/02 ; C07F9/40

Abstract:
The present patent application relates to a process for preparing cinacalcet or a pharmaceutically acceptable salt thereof, which comprises reacting 3-trifluoromethylbenzaldehyde having the following formula (II) with the phosphorus-comprising derivative having the following formula (III) in which R1 and R2, which may be identical or different, are each a (C1-C6)alkyl group. The present invention also relates to the phosphorus-comprising derivative having the formula (III), to the use thereof and to the process for preparing same. The present invention also relates to the phosphate salt of cinacalcet and to uses thereof.
Public/Granted literature
- US20160200664A1 Process for Preparing Cinacalcet and Pharmaceutically Acceptable Salts Thereof Public/Granted day:2016-07-14
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