Invention Grant
- Patent Title: Arginine methyltransferase inhibitors and uses thereof
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Application No.: US14775794Application Date: 2014-03-14
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Publication No.: US09598374B2Publication Date: 2017-03-21
- Inventor: Richard Chesworth , Lorna Helen Mitchell , Gideon Shapiro , Kerren Kalai Swinger
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2014/029710 WO 20140314
- International Announcement: WO2014/153226 WO 20140925
- Main IPC: C07D231/12
- IPC: C07D231/12 ; A61K31/415 ; A61K31/4155 ; C07D401/04 ; C07D403/08 ; C07D405/04 ; C07D405/08 ; C07D405/12 ; C07D493/10 ; C07D403/04
Abstract:
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.
Public/Granted literature
- US20160024016A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Public/Granted day:2016-01-28
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