Invention Grant
- Patent Title: Substituted benzothienyl-pyrrolotriazines and uses thereof in the treatment cancer
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Application No.: US14365024Application Date: 2012-12-11
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Publication No.: US09598416B2Publication Date: 2017-03-21
- Inventor: Marie-Pierre Collin , Dirk Brohm , Mélanie Héroult , Mario Lobell , Walter Hübsch , Klemens Lustig , Sylvia Grünewald , Ulf Bömer , Verena Vöhringer , Niels Lindner
- Applicant: Bayer Intellectual Property GmbH , BAYER PHARMA AKTIENGESELLSCHAFT
- Applicant Address: DE Monheim
- Assignee: BAYER INTELLECTUAL PROPERTY GMBH
- Current Assignee: BAYER INTELLECTUAL PROPERTY GMBH
- Current Assignee Address: DE Monheim
- Agency: Nixon & Vanderhye P.C.
- Priority: EP11193839 20111215
- International Application: PCT/EP2012/075127 WO 20121211
- International Announcement: WO2013/087647 WO 20130620
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D409/04 ; C07D409/14 ; A61K31/53 ; A61K31/382 ; A61P35/00 ; A61K31/5377 ; A61K31/541 ; A61K31/551 ; A61K31/553
Abstract:
This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-fJ[1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.
Public/Granted literature
- US20150080371A1 SUBSTITUTED BENZOTHIENYL - PYRROLOTRIAZINES AND USES THEREOF IN THE TREATMENT CANCER Public/Granted day:2015-03-19
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