- Patent Title: Cell penetrating peptides for intracellular delivery of molecules
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Application No.: US14433573Application Date: 2013-10-04
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Publication No.: US09598465B2Publication Date: 2017-03-21
- Inventor: Gilles Divita , Sebastien Deshayes , Karidia Konate , May Catherine Morris
- Applicant: Centre National de la Recherche Scientifique
- Applicant Address: US CA Pacific Palisades
- Assignee: AADIGEN LLC
- Current Assignee: AADIGEN LLC
- Current Assignee Address: US CA Pacific Palisades
- Agency: Morrison & Foerster LLP
- Priority: WOPCT/IB2012/055344 20121004
- International Application: PCT/EP2013/070680 WO 20131004
- International Announcement: WO2014/053624 WO 20140410
- Main IPC: A61K47/42
- IPC: A61K47/42 ; A61K47/48 ; C07K7/08 ; C07K14/00 ; A61K9/51 ; A61K38/00
Abstract:
A cell-penetrating peptide characterized in that it comprises an amino acid sequence: X1X2X3WWX4X5WAX6X3X7X8X9X10X11X12WX13R (SEQ ID No: 10), wherein X1, is beta-A or S, X2 is L or none, X3 is R or none, X4 is L, R or G, X5 is R, W or S, X6 is S, P or T, X7 is W or P, X8 is F, A or R, X9 is S, L, P or R, X10 is R or S, X11 n is W or none, X12 is A, R or none and X13 is W or F, and wherein if X3 is none, then X3, X11 and X12 are none as well.
Public/Granted literature
- US20160060296A1 Cell Penetrating Peptides for Intracellular Delivery of Molecules Public/Granted day:2016-03-03
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