Invention Grant
- Patent Title: Use of human biliverdin reductase and fragments thereof for the treatment of protein kinase C-delta and ERK related conditions
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Application No.: US14741951Application Date: 2015-06-17
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Publication No.: US09598677B2Publication Date: 2017-03-21
- Inventor: Mahin D. Maines
- Applicant: University of Rochester
- Applicant Address: US NY Rochester
- Assignee: University of Rochester
- Current Assignee: University of Rochester
- Current Assignee Address: US NY Rochester
- Agency: Riverside Law LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C12N9/02 ; A61K38/44 ; A61K31/713 ; C12N5/00

Abstract:
The present invention is directed to methods of modulating PKC-δ activity and PKC-δ/ERK complex activity in cells via biliverdin reductase. Methods and compositions for diagnosing and treating a PKC-δ and PKC-δ/ERK complex related condition are also disclosed.
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