Invention Grant
- Patent Title: Methods for processing coagulation factors
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Application No.: US14342017Application Date: 2012-08-31
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Publication No.: US09598687B2Publication Date: 2017-03-21
- Inventor: Alan Hunter , Xiangyang Wang , Timothy Pabst , Michaela Wendeler , Jihong Wang , Kendall Carey , Robert Strouse , Johnson Varghese
- Applicant: Alan Hunter , Xiangyang Wang , Timothy Pabst , Michaela Wendeler , Jihong Wang , Kendall Carey , Robert Strouse , Johnson Varghese
- Applicant Address: US MD Gaithersburg
- Assignee: MEDIMMUNE, LLC
- Current Assignee: MEDIMMUNE, LLC
- Current Assignee Address: US MD Gaithersburg
- Agent Melissa Pytel
- International Application: PCT/US2012/053319 WO 20120831
- International Announcement: WO2013/036445 WO 20130314
- Main IPC: A61K38/36
- IPC: A61K38/36 ; C07K14/745 ; C07K1/18 ; C07K1/20 ; C07K1/34 ; C07K1/36 ; C12N9/74 ; C12N9/64
Abstract:
The present application relates to methods for purifying recombinant coagulation factor proteins, including for example, prothrombin (Factor II). In embodiments, the methods provide purified prothrombin that exhibit increased bioactivity and reduced levels of thrombin, thereby increasing the safety of the prothrombin. Also provided are purified recombinant coagulation factor proteins.
Public/Granted literature
- US20140303353A1 METHODS FOR PROCESSING COAGULATION FACTORS Public/Granted day:2014-10-09
Information query
IPC分类:
