Invention Grant
- Patent Title: Chemical process for preparing spiroindolones and intermediates thereof
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Application No.: US14384233Application Date: 2013-03-22
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Publication No.: US09598712B2Publication Date: 2017-03-21
- Inventor: Michael Crowe , Michael Foulkes , Giancarlo Francese , Dominique Grimler , Ernst Kuesters , Kurt Laumen , Yunzhong Li , Changxue Lin , Jovana Nazor , Thomas Ruch , Derek Smith , Shiwei Song , Shangjun Teng
- Applicant: Michael Crowe , Michael Foulkes , Giancarlo Francese , Dominique Grimler , Ernst Kuesters , Kurt Laumen , Yunzhong Li , Changxue Lin , Jovana Nazor , Thomas Ruch , Derek Smith , Shiwei Song , Shangjun Teng
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Daniel Woods
- Priority: WOPCT/CN2012/000359 20120323
- International Application: PCT/EP2013/056170 WO 20130322
- International Announcement: WO2013/139987 WO 20130926
- Main IPC: C07D209/12
- IPC: C07D209/12 ; C07D209/16 ; C12P17/10 ; C07D405/06 ; C07D471/20 ; C07D209/14 ; C07D209/34 ; C12N9/10 ; C07D209/38
Abstract:
The present invention relates to processes and intermediates useful for the manufacture of spiroindolone compounds such as (1′R,3′S)-5,7′-dichloro-6′-fluoro-3′-methyl-2′,3′,4′,9′-tetrahydrospiro[indoline-3,1′-pyrido[3,4-b]indol]-2-one and salts and hydrates and solvates thereof.
Public/Granted literature
- US20150045562A1 Chemical Process for Preparing Spiroindolones and Intermediates Thereof Public/Granted day:2015-02-12
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