Users are enabled to define and modify mappings between (1) gestures and (2) actions performed by one or more computing devices in response to a device detecting performance of a gesture. A generalized gesture-to-action mapping framework allows users to intuitively define and modify such mappings. In response to a device detecting the performance of a particular gesture, one or more devices may cause the execution of one or more device actions based on a set of user-defined gesture-to-action mappings.