Methods and systems of symbol level interference cancellation at a receiver for multiuser detection is provided. In an embodiment, the method includes performing an interference cancellation based decoding for a plurality of users through a plurality of iterations for generating a plurality of soft bit estimates for each of the users during each of the iterations. Each of the iterations involves sequential cancellation of each of the user signals for performing interference cancellation based decoding for each subsequent user other than a first user. The method also includes re-using the generated plurality of soft bit estimates for performing each subsequent iteration of the interference cancellation based decoding of the plurality of users. A plurality of soft bit estimates associated with each user generated during an (N−1)th iteration is re-used during an Nth iteration for the user, N being a whole number with a minimum value of 2.