NFC-enabled systems and devices 110, 120, 950, and related methods 1400, for determining the orientation of an NFC-enabled mobile device within a covering 10. The orientation determination may include determining which way each face of an NFC-enabled mobile device 110, 120 is facing in the covering 10, and which end of the NFC-enable device is oriented in which way in the covering, through the use of particular arrangements of at least one NFC device attached to the covering and at least one NFC antenna of the NFC-enabled mobile device. By determining the orientation of the NFC-enabled device within the covering, the NFC-enabled device may then be configured for executing a particular command, such as to optimize some aspect of the NFC-enabled device based on the device orientation.