Invention Grant
- Patent Title: Enteral administration of sorbent polymer for treatment and prophylaxis of inflammation
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Application No.: US14025322Application Date: 2013-09-12
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Publication No.: US09603807B2Publication Date: 2017-03-28
- Inventor: John A. Kellum , Mitchell P. Fink
- Applicant: University of Pittsburgh—Of the commonwealth System of Higher Education
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: A61K9/50
- IPC: A61K9/50 ; A61K31/75 ; A61K31/79 ; A61K31/745 ; A61K9/20 ; A61K9/00
Abstract:
The invention provides a method of ameliorating inflammation in a patient involving administering to the patient a therapeutically effective dose of composition including polystyrene divinyl benzene copolymer and a polyvinyl pyrrolidone polymer. More particularly, the method relates to using these polymers as an enteral sorbent preparation to remove inflammatory mediators, such as cytokines, from the intestinal lumen. The polymers can be in the form of a preparation of polystyrene divinyl benzene copolymer beads with a biocompatible polyvinyl pyrrolidone polymer coating.
Public/Granted literature
- US20140017309A1 ENTERAL ADMINISTRATION OF SORBENT POLYMER FOR TREATMENT AND PROPHYLAXIS OF INFLAMMATION Public/Granted day:2014-01-16
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