Invention Grant
- Patent Title: Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors
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Application No.: US14711911Application Date: 2015-05-14
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Publication No.: US09603836B2Publication Date: 2017-03-28
- Inventor: Stefano Crosignani , Sandra Cauwenberghs , Gregory Driessens , Frederik Deroose
- Applicant: ITEOS THERAPEUTICS
- Applicant Address: BE Charleroi
- Assignee: ITEOS THERAPEUTICS
- Current Assignee: ITEOS THERAPEUTICS
- Current Assignee Address: BE Charleroi
- Agency: Howson & Howson LLP
- Agent David A. Rubin; Cathy A. Kodroff
- Priority: EP14168534 20140515; BE2014/0754 20141021
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D207/40 ; C07D207/408 ; A61K31/404 ; A61K31/4015

Abstract:
The present invention relates to compound of Formula I or pharmaceutically acceptable enantiomers, salts, solvates or prodrugs thereof. The invention further relates to the use of the compounds of Formula I as IDO1 inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer and endometriosis. The invention also relates to a process for manufacturing compounds of Formula I.
Public/Granted literature
- US20150329525A1 PYRROLIDINE-2, 5-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE AS IDO1 INHIBITORS Public/Granted day:2015-11-19
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