Invention Grant
- Patent Title: Layer-by-layer stereocomplexed polymers as drug depot carriers or coatings in medical devices
-
Application No.: US12037307Application Date: 2008-02-26
-
Publication No.: US09603980B2Publication Date: 2017-03-28
- Inventor: Jonathon Z. Zhao
- Applicant: Jonathon Z. Zhao
- Applicant Address: CH
- Assignee: Cardinal Health Switzerland 515 GmbH
- Current Assignee: Cardinal Health Switzerland 515 GmbH
- Current Assignee Address: CH
- Main IPC: A61L31/16
- IPC: A61L31/16 ; A61L31/10

Abstract:
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaque, and atherosclerosis in type 2 diabetic patients. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned.
Public/Granted literature
- US20090214615A1 LAYER - BY - LAYER STEREOCOMPLEXED POLYMERS AS DRUG DEPOT CARRIERS OR COATINGS IN MEDICAL DEVICES Public/Granted day:2009-08-27
Information query