Invention Grant
- Patent Title: Indolinone compounds and uses thereof
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Application No.: US14877708Application Date: 2015-10-07
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Publication No.: US09604927B2Publication Date: 2017-03-28
- Inventor: Jean-Michel Vernier
- Applicant: Tokalas, Inc.
- Applicant Address: US CA San Diego
- Assignee: Oncternal Therapeutics, Inc.
- Current Assignee: Oncternal Therapeutics, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Knobbe Martens Olson & Bear, LLP
- Main IPC: C07D209/38
- IPC: C07D209/38 ; A61K31/404 ; C07D401/06 ; C07D401/10 ; C07D403/10 ; C07D209/34
Abstract:
Indolinone derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indolinone derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.
Public/Granted literature
- US20160102055A1 INDOLINONE COMPOUNDS AND USES THEREOF Public/Granted day:2016-04-14
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