Invention Grant
- Patent Title: 2-aminopyrazine derivatives as CSF-1R kinase inhibitors
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Application No.: US14411024Application Date: 2013-06-26
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Publication No.: US09604940B2Publication Date: 2017-03-28
- Inventor: Stephen John Davies , Stephane Pintat , Carl Leslie North , David Festus Charles Moffat
- Applicant: Chroma Therapeutics Ltd.
- Applicant Address: GB Abingdon, Oxfordshire
- Assignee: Chroma Therapeutics Ltd.
- Current Assignee: Chroma Therapeutics Ltd.
- Current Assignee Address: GB Abingdon, Oxfordshire
- Agency: Norton Rose Fulbright US LLP
- Priority: GB1211310.6 20120626
- International Application: PCT/GB2013/051693 WO 20130626
- International Announcement: WO2014/001802 WO 20140103
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; C07D241/20 ; C07D401/12 ; C07D403/12 ; C07D401/14 ; C07D403/10 ; C07D403/04
Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, N-oxide, hydrate or solvate thereof: wherein: ring A, R1, R2, n, X, V, W, Z, ring B, [Linker] and R areas defined herein. The compounds are useful as inhibitors of CSF-1R kinase. The compounds can thus be used in medicine.
Public/Granted literature
- US20150368210A1 2-AMINOPYRAZINE DERIVATIVES AS CSF-1 R KINASE INHIBITORS Public/Granted day:2015-12-24
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