Invention Grant
- Patent Title: Substituted 5-imino-1,2,4-thiadiazoles that can be used to treat neurodegenerative diseases
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Application No.: US13499901Application Date: 2010-10-04
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Publication No.: US09604947B2Publication Date: 2017-03-28
- Inventor: Ana Martínez Gil , Carmen Gil Ayuso-Gontan , Valle Palomo Ruiz , Daniel Perez Fernandez , Concepción Perez Martín , Ana María Perez Castillo , María Isabel Loza Garcia , María Isabel Cadavid Torres , José Brea Floriani
- Applicant: Ana Martínez Gil , Carmen Gil Ayuso-Gontan , Valle Palomo Ruiz , Daniel Perez Fernandez , Concepción Perez Martín , Ana María Perez Castillo , María Isabel Loza Garcia , María Isabel Cadavid Torres , José Brea Floriani
- Applicant Address: ES Madrid
- Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
- Current Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
- Current Assignee Address: ES Madrid
- Agency: Blakely Sokoloff Taylor & Zafman LLP
- Priority: ES200930787 20091002
- International Application: PCT/ES2010/070641 WO 20101004
- International Announcement: WO2011/039403 WO 20110407
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A01N43/40 ; A61K31/44 ; A61K31/41 ; A01N43/82 ; C07D285/08 ; A61K31/433
Abstract:
The present invention is based on the use of a broad family of 5-imino-1,2,4-thiadiazoles as potential new drugs for the treatment of diseases in which PDE7 inhibition is important, specially inflammatory diseases, autoimmune and neurodegenerative disorders. On the other hand, compounds of the 5-imino-1,2,4-thiadiazole family are here described, as well as their synthetic procedures, and they may have great application as drug or drug candidates.Therefore, a first aspect of the present invention is related to a compound of formula (I):
Public/Granted literature
- US20120225879A1 SUBSTITUTED 5-IMINO-1,2,4-THIADIAZOLES THAT CAN BE USED TO TREAT NEURODEGENERATIVE DISEASES Public/Granted day:2012-09-06
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