Invention Grant
- Patent Title: Compounds as modulator of JAK-STAT pathway, methods and applications thereof
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Application No.: US15004114Application Date: 2016-01-22
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Publication No.: US09604974B2Publication Date: 2017-03-28
- Inventor: Kanchugarakoppal Subbegowda Rangappa , Basappa , Chakrabhavi Dhananjaya Mohan , Shobith Rangappa , Hanumantharayappa Bharathkumar , Gautam Sethi , Andreas Bender , Peter Edward Lobie , Kam Man Hui , Alan Prem Kumar , Vijay Kumar Pandey , Julian Fuchs , Muthu Kumaraswamy Shanmugam , Krishna Bulusu , Xiaoyun Dai , Feng Li , Amudha Deivasigamani
- Applicant: UNIVERSITY OF MYSORE , NATIONAL UNIVERSITY OF SINGAPORE , BANGALORE UNIVERSITY , CAMBRIDGE ENTERPRISE LTD
- Applicant Address: IN Karnataka SG Singapore IN Karnataka GB Cambridge
- Assignee: UNIVERSITY OF MYSORE,NATIONAL UNIVERSITY OF SINGPORE,BANGALORE UNIVERSITY,CAMBRIDGE ENTERPRISE LTD
- Current Assignee: UNIVERSITY OF MYSORE,NATIONAL UNIVERSITY OF SINGPORE,BANGALORE UNIVERSITY,CAMBRIDGE ENTERPRISE LTD
- Current Assignee Address: IN Karnataka SG Singapore IN Karnataka GB Cambridge
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: IN324/CHE/2015 20150122
- Main IPC: C07D413/04
- IPC: C07D413/04 ; C07D265/16

Abstract:
The present disclosure relates to compound of structural Formula I and a method for preparing said compounds. The disclosure further relates to a method of employing the Formula I compounds for modulation of Janus kinase-Signal Transducer and Activator of Transcription (JAK-STAT) pathway in cancer cells, and the corresponding use of compound of Formula I as anti-cancer agents.
Public/Granted literature
- US20160214968A1 COMPOUNDS AS MODULATOR OF JAK-STAT PATHWAY, METHODS AND APPLICATIONS THEREOF Public/Granted day:2016-07-28
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