Invention Grant
- Patent Title: Glycomimetics to inhibit pathogen-host interactions
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Application No.: US14385312Application Date: 2013-03-14
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Publication No.: US09605014B2Publication Date: 2017-03-28
- Inventor: Robert J. Woods , Paul V. Murphy , Loretta Yang , Hannah M. K. Smith , Jenifer Hendel
- Applicant: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. , NATIONAL UNIVERSITY OF IRELAND, GALWAY , GLYCOSENSORS AND DIAGNOSTICS, LLC.
- Applicant Address: US GA Athens IE Galway US GA Athens
- Assignee: University of Georgia Research Foundation, Inc.,National University of Ireland, Galway,Glycosensors and Diagnostics, LLC.
- Current Assignee: University of Georgia Research Foundation, Inc.,National University of Ireland, Galway,Glycosensors and Diagnostics, LLC.
- Current Assignee Address: US GA Athens IE Galway US GA Athens
- Agency: Mueting, Raasch & Gebhardt, P.A.
- International Application: PCT/US2013/031238 WO 20130314
- International Announcement: WO2013/138563 WO 20130919
- Main IPC: C07H17/04
- IPC: C07H17/04 ; C07H15/20 ; C07H17/02 ; C07H19/01 ; C07H19/02 ; C07H19/04 ; C07H19/24 ; C07H15/04 ; C07D455/02 ; G06F19/10
Abstract:
The present invention relates to novel glycomimetic compounds that are rationally designed to inhibit the binding of various pathogens to cell surface sialylated galactose and methods of use thereof. Specifically sialic acid glycosides and C-glycosides are disclosed that form a lactam ring structure or a cyclic ether/amine ring structure with the adjacent monosaccharide residue.
Public/Granted literature
- US20150072952A1 GLYCOMIMETICS TO INHIBIT PATHOGEN-HOST INTERACTIONS Public/Granted day:2015-03-12
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