Invention Grant
- Patent Title: Rapid selection method for HIV gp-120 variants
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Application No.: US14000924Application Date: 2012-02-24
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Publication No.: US09605030B2Publication Date: 2017-03-28
- Inventor: María Eloísa Yuste Herranz , Víctor Sánchez Merino , Carolina Ferreira
- Applicant: María Eloísa Yuste Herranz , Víctor Sánchez Merino , Carolina Ferreira
- Applicant Address: ES Barcelona ES Badalona
- Assignee: LABORATORIOS DEL DR. ESTEVE, S.A.,FUNDACIÓ PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
- Current Assignee: LABORATORIOS DEL DR. ESTEVE, S.A.,FUNDACIÓ PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
- Current Assignee Address: ES Barcelona ES Badalona
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Priority: EP11382051 20110225
- International Application: PCT/EP2012/053185 WO 20120224
- International Announcement: WO2012/113921 WO 20120830
- Main IPC: C07K14/16
- IPC: C07K14/16 ; G01N33/68 ; C07K14/005 ; C12N15/10 ; C07K16/10 ; G01N33/569 ; A61K39/00
Abstract:
The invention relates to a method for rapid immunogen selection (RIS) based on the binding a library of recombinant viruses containing randomized HIV gp120 variants of a surface polypeptide displayed to said neutralizing antibodies. The invention relates as well to the use of the HIV gp120 immunogens isolated according to the RIS method of the invention in medicine for the treatment of diseases caused by a virus and in diagnosis for the identification of neutralizing antibodies in a patient.
Public/Granted literature
- US20140037667A1 RAPID SELECTION METHOD FOR HIV GP-120 VARIANTS Public/Granted day:2014-02-06
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