Invention Grant
- Patent Title: Compositions and methods for treating hypertension
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Application No.: US14390408Application Date: 2013-04-03
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Publication No.: US09605047B2Publication Date: 2017-03-28
- Inventor: Bradley Maron , Joseph Loscalzo , Jane Leopold
- Applicant: The Brigham and Women's Hospital, Inc.
- Applicant Address: US MA Boston
- Assignee: The Brigham and Womens's Hospital, Inc.
- Current Assignee: The Brigham and Womens's Hospital, Inc.
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- International Application: PCT/US2013/035075 WO 20130403
- International Announcement: WO2013/152076 WO 20131010
- Main IPC: C07K14/705
- IPC: C07K14/705 ; G01N33/50 ; A61K38/17 ; A61K38/00
Abstract:
The technology described herein is directed to agents that reduce the level of oxidant-modified ET-B Cys405, Cys403, or Cys402 and the identification and use of such agents for, e.g. to treat hypertension.
Public/Granted literature
- US20150203563A1 COMPOSITIONS AND METHODS FOR TREATING HYPERTENSION Public/Granted day:2015-07-23
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