Invention Grant
- Patent Title: Composition and method for treating a tauopathy
-
Application No.: US12906617Application Date: 2010-10-18
-
Publication No.: US09605054B2Publication Date: 2017-03-28
- Inventor: Scott T. Brady , Lester I. Binder , Gerardo Andres Morfini , Nicholas M. Kanaan , Nichole E. LaPointe
- Applicant: Scott T. Brady , Lester I. Binder , Gerardo Andres Morfini , Nicholas M. Kanaan , Nichole E. LaPointe
- Applicant Address: US IL Urbana US IL Evanston
- Assignee: The Board of Trustees of the University of Illinois,Northwestern University
- Current Assignee: The Board of Trustees of the University of Illinois,Northwestern University
- Current Assignee Address: US IL Urbana US IL Evanston
- Agency: Licata & Tyrrell P.C.
- Main IPC: C07K7/00
- IPC: C07K7/00 ; A61K38/10 ; A61K39/395 ; C07K16/18 ; C07K14/47 ; G01N33/50 ; A61K38/00
Abstract:
The present invention is a composition and method for the prevention and treatment of a tauopathy. The composition of the invention includes N-terminal amino acid residues of the tau protein, which have been identified as being involved in toxic activation of a PP1/GSK3 signaling cascade and inhibition of fast axonal transport in human tauopathies.
Public/Granted literature
- US20120142602A1 Composition and Method for Preventing or Treating a Tauopathy Public/Granted day:2012-06-07
Information query
