Invention Grant
- Patent Title: Methods of detecting mutations in BRAF and epigenetic changes
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Application No.: US14363182Application Date: 2012-12-06
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Publication No.: US09605312B2Publication Date: 2017-03-28
- Inventor: Wim Van Criekinge , James Clark , Johan Vandersmissen
- Applicant: MDxHealth SA
- Applicant Address: BE Sart-Tilman (Liege)
- Assignee: MDxHealth, SA
- Current Assignee: MDxHealth, SA
- Current Assignee Address: BE Sart-Tilman (Liege)
- Agency: Andrus Intellectual Property Law, LLP
- International Application: PCT/IB2012/003094 WO 20121206
- International Announcement: WO2013/084075 WO 20130613
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Disclosed are methods for assessing the methylation and mutation status of nucleic acid in a sample. The methods provide for methylation-dependent modification of the nucleic acid in a sample, and subsequently nucleic acid amplification processes to distinguish between mutated and non-mutated target sequence.
Public/Granted literature
- US20140322714A1 Methods of Detecting Mutations and Epigenetic Changes Public/Granted day:2014-10-30
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