A pressurization control system configured to regulate air pressure with a space includes an air supply source fluidly coupled to a damper, a room controller configured to provide a control signal to the damper. The room controller includes a flow controller configured to generate a flow feedback signal, and a pressure controller configured to generate a pressure feedback signal, wherein the room controller is configured to receive flow and pressure feedback signals and generate the control signal based on one or more of the received flow and pressure feedback signals.