A method and a device for locking and unlocking with a touch graphic are provided. The method includes: outputting a randomly changed graphic receiving interface; receiving a touch graphic input by a user by touching through the graphic receiving interface; and performing a locking or unlocking operation according to the touch graphic. The device includes: an interface outputting module configured to output a randomly changed graphic receiving interface; a receiving module configured to receive a touch graphic input by a user by touching through the graphic receiving interface; and a locking and unlocking module configured to perform a locking or unlocking operation according to the touch graphic. The present invention improves security of locking or unlocking with a touch graphic.