Devices, systems, and methods of communicating information directly to a sequencer or a buffer in a memory device are provided. In some embodiments, instructions are sent directly from an external processor to a sequencer in the memory device, and the sequencer configures the instructions for an internal processor, such as one or more arithmetic logic units (ALUs) embedded on the memory device. Further, data to be operated on by the internal processor can be sent directly from the external processor to a buffer, and the sequencer can copy the data from the buffer to the internal processor. As power can be consumed each time a memory array is written to or read from, the direct communication of instructions and/or data can reduce the power consumed in writing to or reading from the memory array.