An all-optical time slice switching method based on time synchronization is provided. With the method, continuous data streams in an optical network are assembled to time domain periodic optical time slices and are transmitted in an asynchronous transmission mode. Network nodes obtain high precision synchronization time via a network and control optical switches to switch arriving optical time slices to a target port at precise time points periodically, therefore all-optical switching is implemented. When a connection request arrives, an available path, a wavelength and time slots to be occupied are calculated by a source node according to information on available time slots of the optical network, and the time slots are reserved by a connection management module. After the time slots are reserved, the source node send optical time slices carrying services periodically at reserved time slots. A destination node restores the optical time slices to the data streams.