Invention Grant
- Patent Title: Methods, compositions and kits for vegetative cell-based vaccines and spore-based vaccines
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Application No.: US12987280Application Date: 2011-01-10
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Publication No.: US09610333B2Publication Date: 2017-04-04
- Inventor: John E. Herrmann , Boris R. Belitsky , Abraham L. Sonenshein , Saul Tzipori
- Applicant: John E. Herrmann , Boris R. Belitsky , Abraham L. Sonenshein , Saul Tzipori
- Applicant Address: US MA Boston
- Assignee: Tufts University
- Current Assignee: Tufts University
- Current Assignee Address: US MA Boston
- Agency: Lawson & Weitzen LLP
- Agent Sonia K. Guterman
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/08 ; A61K39/15 ; A61K39/12 ; A61K35/742
Abstract:
Methods for immunizing a subject to an antigen of an infectious agent, a tumor, or an allergen are provided, using vegetative cytoplasmic expression of the antigen or spore surface display of the antigen, and contacting the subject with a composition including a spore or a vegetative cell or both with or without an adjuvant. Also included are thermally-stable vaccine compositions using the method described above and kits including the compositions.
Public/Granted literature
- US20110104200A1 Methods, compositions and kits for vegetative cell-based vaccines and spore-based vaccines Public/Granted day:2011-05-05
Information query
