Invention Grant
- Patent Title: Methods and compositions related to annexin 1-binding compounds
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Application No.: US13515930Application Date: 2010-12-23
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Publication No.: US09610359B2Publication Date: 2017-04-04
- Inventor: Michiko Fukuda , Kazuhiro Sugihara , Naohira Kanayama
- Applicant: Michiko Fukuda , Kazuhiro Sugihara , Naohira Kanayama
- Applicant Address: US CA La Jolla JP Shizuoka
- Assignee: Burnham Institute for Medical Research,Hamamatsu University School of Medicine
- Current Assignee: Burnham Institute for Medical Research,Hamamatsu University School of Medicine
- Current Assignee Address: US CA La Jolla JP Shizuoka
- Agency: Lewis Kohn & Walker LLP
- Agent David M. Kohn; Kari Moyer-Henry
- International Application: PCT/US2010/062072 WO 20101223
- International Announcement: WO2011/079304 WO 20110630
- Main IPC: A61K38/08
- IPC: A61K38/08 ; A61K49/00 ; C07K7/06 ; A61P35/00 ; A61K47/48

Abstract:
Disclosed are conjugates comprising the annexin 1-binding peptide IFLLWQR covalently linked to a therapeutic or detectable agent. Also disclosed are compositions comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are isolated nucleic acids comprising a nucleic acid sequence encoding a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods comprising administering to a subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods of targeting a tumor cell in a subject comprising administering to the subject a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods of targeting a tumor cell in a subject comprising administering to the subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. The disclosed targeting is useful for treatment of, for example, cancer.
Public/Granted literature
- US20120251453A1 Methods and Compositions Related to Annexin 1-Binding Compounds Public/Granted day:2012-10-04
Information query
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