Invention Grant
- Patent Title: Cyclodextrin and antibody-drug conjugate formulations
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Application No.: US14774372Application Date: 2014-03-12
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Publication No.: US09610361B2Publication Date: 2017-04-04
- Inventor: Hui Li , Shan Jiang , Mary Wallace , Damon Meyer
- Applicant: Seattle Genetics, Inc.
- Applicant Address: US WA Bothell
- Assignee: Seattle Genetics, Inc.
- Current Assignee: Seattle Genetics, Inc.
- Current Assignee Address: US WA Bothell
- Agency: Seattle Genetics, Inc.
- International Application: PCT/US2014/024466 WO 20140312
- International Announcement: WO2014/165119 WO 20141009
- Main IPC: C07K19/00
- IPC: C07K19/00 ; A61K47/48 ; C07D519/00 ; A61K31/5517 ; A61K47/40 ; B01D61/14
Abstract:
Disclosed are formulations, including both liquid and lyophilized formulations, comprising a benzodiazepine anti-body-drug conjugate (ADC) and a cyclodextrin. Also disclosed are methods of purifying mixtures comprising benzodiazepine anti-body-drug conjugates and process drug-related impurities.
Public/Granted literature
- US20160045615A1 CYCLODEXTRIN AND ANTIBODY-DRUG CONJUGATE FORMULATIONS Public/Granted day:2016-02-18
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