Invention Grant
- Patent Title: Inhibitors of histone demethylases
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Application No.: US14381558Application Date: 2013-10-01
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Publication No.: US09611219B2Publication Date: 2017-04-04
- Inventor: Marc Labelle , Thomas Boesen , Mukund Mehrotra , Qasim Khan , Farman Ullah
- Applicant: EpiTherapeutics ApS
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Priority: DK201200599 20121002; DK201370112 20130227
- International Application: PCT/EP2013/070457 WO 20131001
- International Announcement: WO2014/053491 WO 20140410
- Main IPC: A61K31/00
- IPC: A61K31/00 ; A61K31/44 ; C07D213/44 ; C07D401/00 ; C07D421/00 ; C07D413/00 ; C07D405/00 ; C07D213/79 ; C07D401/12 ; C07D405/12 ; C07D413/12 ; A61K31/443 ; A61K31/4439 ; A61K31/4545 ; A61K31/496 ; C07D401/06 ; A61K31/444
Abstract:
The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament. The compounds take the form (I)
Public/Granted literature
- US20150203453A1 INHIBITORS OF HISTONE DEMETHYLASES Public/Granted day:2015-07-23
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