- Patent Title: Diarylalkylamine REV-ERB antagonists and their use as medicaments
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Application No.: US15027951Application Date: 2014-10-09
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Publication No.: US09611245B2Publication Date: 2017-04-04
- Inventor: Benedetto Grimaldi , Esther Torrente , Rita Scarpelli , Giovanni Bottegoni , Tiziano Bandiera , Marina Veronesi
- Applicant: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
- Applicant Address: IT Genoa
- Assignee: Fondazione Istituto Italiano Di Tecnologia
- Current Assignee: Fondazione Istituto Italiano Di Tecnologia
- Current Assignee Address: IT Genoa
- Agency: Seed IP Law Group LLP
- Priority: ITTO2013A0816 20131009
- International Application: PCT/EP2014/071654 WO 20141009
- International Announcement: WO2015/052283 WO 20150416
- Main IPC: C07D333/20
- IPC: C07D333/20 ; C07D309/14 ; C07D211/58 ; C07D295/08 ; C07D295/16
Abstract:
The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses as anti-proliferative and pro-apoptotic agents for cancer therapy.
Public/Granted literature
- US20160237057A1 DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS Public/Granted day:2016-08-18
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