Invention Grant
- Patent Title: 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
-
Application No.: US14373100Application Date: 2013-02-07
-
Publication No.: US09611249B2Publication Date: 2017-04-04
- Inventor: Maria Alessandra Alisi , Nicola Cazzolla , Patrizia Dragone , Guido Furlotti , Caterina Maugeri , Rosella Ombrato , Francesca Mancini
- Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
- Applicant Address: IT Rome
- Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
- Current Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
- Current Assignee Address: IT Rome
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP12156292 20120212
- International Application: PCT/EP2013/052400 WO 20130207
- International Announcement: WO2013/124158 WO 20130829
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D405/14 ; C07D413/14
Abstract:
The present invention relates to the 1H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta (GSK-3β) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.
Public/Granted literature
- US20150057294A1 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS Public/Granted day:2015-02-26
Information query
