Invention Grant
- Patent Title: PRMT5 inhibitors and uses thereof
-
Application No.: US14654276Application Date: 2013-12-20
-
Publication No.: US09611257B2Publication Date: 2017-04-04
- Inventor: Kenneth W. Duncan , Richard Chesworth , Michael John Munchhof
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2013/077221 WO 20131220
- International Announcement: WO2014/100716 WO 20140626
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07D401/14 ; C07D413/14 ; C07D401/06 ; C07D413/06
Abstract:
Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.
Public/Granted literature
- US20150344463A1 PRMT5 INHIBITORS AND USES THEREOF Public/Granted day:2015-12-03
Information query
