Invention Grant
- Patent Title: Soluble guanylate cyclase activators
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Application No.: US15103140Application Date: 2014-12-05
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Publication No.: US09611278B2Publication Date: 2017-04-04
- Inventor: Xiaoqing Han , Alan Whitehead , Subharekha Raghavan , Jonathan Groeper , Jian Guo , Yong Zhang
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A Meade; Anna L. Cocuzzo
- International Application: PCT/US2014/068688 WO 20141205
- International Announcement: WO2015/088885 WO 20150618
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/52 ; A61K45/06 ; C07D519/00

Abstract:
A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula I or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20160304536A1 SOLUBLE GUANYLATE CYCLASE ACTIVATORS Public/Granted day:2016-10-20
Information query
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