Invention Grant
- Patent Title: Method for increasing granulocyte number in a patient by administering superactive IL-33 fragments
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Application No.: US14001271Application Date: 2012-02-24
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Publication No.: US09611307B2Publication Date: 2017-04-04
- Inventor: Jean-Philippe Girard , Corinne Cayrol-Girard , Emma Lefrancais
- Applicant: Jean-Philippe Girard , Corinne Cayrol-Girard , Emma Lefrancais
- Applicant Address: FR Paris
- Assignee: Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR Paris
- Agency: Crowell & Moring LLP
- Priority: FR1151498 20110224
- International Application: PCT/EP2012/053199 WO 20120224
- International Announcement: WO2012/113927 WO 20120830
- Main IPC: A61K38/20
- IPC: A61K38/20 ; C07K14/54 ; C07K16/24 ; G01N33/68
Abstract:
The present invention discloses novel active polypeptide fragments of human IL-33 corresponding to natural forms generated by the proteases of human neutrophils (cathepsin G, elastase 2, proteinase 3), as well as the use thereof as a drug, in particular for the treatment of infectious diseases, inflammatory diseases, atherosclerosis, cardiovascular diseases, obesity, or cancer.
Public/Granted literature
- US20140099280A1 Novel Superactive IL-33 Fragments, and Uses Thereof Public/Granted day:2014-04-10
Information query
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