Invention Grant
- Patent Title: Anti-DR5 family antibodies, bispecific or multivalent anti-DR5 family antibodies and methods of use thereof
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Application No.: US14413194Application Date: 2013-07-09
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Publication No.: US09611327B2Publication Date: 2017-04-04
- Inventor: Claudine Brigitte Fernande Vermot-Desroches , Olivier Frédéric Subiger , Laurence Françoise Jeanne-Marie Bourdin
- Applicant: INTERNATIONAL—DRUG—DEVELOPMENT—BIOTECH
- Applicant Address: NL Utrecht
- Assignee: GENMAB B.V.
- Current Assignee: GENMAB B.V.
- Current Assignee Address: NL Utrecht
- Agency: Lathrop & Gage LLP
- Agent James H. Velema, Esq.
- Priority: EP12305821 20120709
- International Application: PCT/EP2013/064466 WO 20130709
- International Announcement: WO2014/009358 WO 20140116
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30 ; A61K39/395 ; A61K39/00

Abstract:
Anti-DR5 family member antibodies and bispecific antibodies comprising one or more anti-DR5 family member antibodies are disclosed. These antibodies can be used to trigger cell death on DR5 positive cells.
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