Invention Grant
- Patent Title: Drug loading pentablock polymers
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Application No.: US14891574Application Date: 2014-05-16
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Publication No.: US09611353B2Publication Date: 2017-04-04
- Inventor: Ashim K. Mitra , Sulabh P. Patel , Ravi D. Vaishya , Vibhuti Agrahari
- Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURI
- Applicant Address: US MO Columbia
- Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
- Current Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
- Current Assignee Address: US MO Columbia
- Agency: Stinson Leonard Street LLP
- International Application: PCT/US2014/038340 WO 20140516
- International Announcement: WO2014/186669 WO 20141120
- Main IPC: C08G63/91
- IPC: C08G63/91 ; A61K9/06 ; A61K9/51 ; C08G63/664
Abstract:
Novel pentablock polymers having a PCL-PLA-PEG-PLA-PCL or PCL-PGA-PEG-PGA-PCL configuration, wherein PEG is polyethylene glycol, PCL is poly(8-caprolactone), PGA is poly(glycolic acid), and PLA is poly(lactic acid), and methods of making nanoparticles from the pentablock polymers, are disclosed. The invention is also directed to a method for preparing nanoparticle compositions comprised of polymers with high levels of bioactive or diagnostic agents.
Public/Granted literature
- US20160090444A1 DRUG LOADING PENTABLOCK POLYMERS Public/Granted day:2016-03-31
Information query
