Invention Grant
- Patent Title: Prophylactic and/or therapeutic agent for inflammatory disease, and method for screening prophylactic and/or therapeutic drug for inflammatory disease
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Application No.: US14783713Application Date: 2014-04-11
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Publication No.: US09611475B2Publication Date: 2017-04-04
- Inventor: Tetsuji Naka , Minoru Fujimoto , Satoshi Serada
- Applicant: National Institutes of Biomedical Innovation, Health and Nutrition
- Applicant Address: JP Osaka
- Assignee: National Institutes of Biomedical Innovation, Health and Nutrition
- Current Assignee: National Institutes of Biomedical Innovation, Health and Nutrition
- Current Assignee Address: JP Osaka
- Agency: Seed IP Law Group LLP
- Priority: JP2013-083397 20130411
- International Application: PCT/JP2014/060552 WO 20140411
- International Announcement: WO2014/168247 WO 20141016
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C12N15/113 ; A61K31/7088 ; A61K31/7105 ; A61K31/711 ; C07K16/18 ; G01N33/50 ; A61K45/06 ; A61K49/00 ; C12Q1/68 ; A01K67/027 ; C07H21/02 ; C07H21/04
Abstract:
Provided are a novel prophylactic and/or therapeutic drug for an inflammatory disease and a method for searching for the same.A prophylactic and/or therapeutic agent for an inflammatory disease that comprises a substance capable of inhibiting the expression or function of leucine rich alpha 2 glycoprotein (LRG). A method of screening for an anti-inflammatory substance using LRG or an LRG-expressing cell, wherein the inhibition of the expression or function of LRG is used as an index.
Public/Granted literature
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