Invention Grant
- Patent Title: Constructs and method for regulating gene expression or for detecting and controlling a DNA locus in eukaryotes
-
Application No.: US14006743Application Date: 2012-03-23
-
Publication No.: US09611486B2Publication Date: 2017-04-04
- Inventor: Kerstin Bystricky , Franck Gallardo , David Lane , Nelly Dubarry
- Applicant: Kerstin Bystricky , Franck Gallardo , David Lane , Nelly Dubarry
- Applicant Address: FR Paris
- Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee Address: FR Paris
- Agency: Hultquist, PLLC
- Agent Mary B. Grant
- Priority: FR1152473 20110324
- International Application: PCT/EP2012/055258 WO 20120323
- International Announcement: WO2012/127047 WO 20120927
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N15/82 ; C12N15/85 ; C07K14/21 ; C12N15/81 ; C12N5/07 ; C12N5/071 ; C12N5/10
Abstract:
The present invention concerns constructs based on sequences derived from the partitioning system of plasmid and chromosomal DNA of bacteria, such as eukaryotic expression vectors, fusion proteins and polynucleotides encoding the same and also eukaryotic cells transformed with or expressing such constructs. The present invention also concerns the use thereof in the regulation of gene expression and/or in the detection and control of the dynamics, localization or metabolism of genomic DNA loci of interest in eukaryotic cells.
Public/Granted literature
Information query
IPC分类:
