Invention Grant
- Patent Title: Biological method for producing cis-5-hydroxy-L-pipecolic acid
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Application No.: US14407576Application Date: 2013-06-12
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Publication No.: US09611490B2Publication Date: 2017-04-04
- Inventor: Tadashi Fujii , Keisuke Tamura
- Applicant: MicroBiopharm Japan Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: MicroBiopharm Japan Co., Ltd.
- Current Assignee: MicroBiopharm Japan Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: JP2012-133876 20120613
- International Application: PCT/JP2013/066218 WO 20130612
- International Announcement: WO2013/187438 WO 20131219
- Main IPC: C12P17/12
- IPC: C12P17/12 ; C12N9/02

Abstract:
A method for producing cis-5-hydroxy-L-pipecolic acid is described. A gene recombinant microorganism enabling direct production of cis-5-hydroxy-L-pipecolic acid can be used in the method. Also described is a gene recombinant microorganism. In particular, it is described that a gene recombinant microorganism having DNAs encoding proteins involved in the biosynthesis of L-pipecolic acid and a DNA encoding a protein having the L-pipecolic acid cis-5-hydroxylase activity is cultured in a medium, and cis-5-hydroxy-L-pipecolic acid is collected from the medium.
Public/Granted literature
- US20150211035A1 BIOLOGICAL METHOD FOR PRODUCING CIS-5-HYDROXY-L-PIPECOLIC ACID Public/Granted day:2015-07-30
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